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The use of OxyContin was associated with an average 2.3 day reduction in inpatient services among patients following total knee arthroplasty (Cheville et al., 2001). In addition data from two retrospective database studies have shown OxyContin to have economic advantages among the long-acting opioids. The first study showed that starting pain treatment using OxyContin for chronic pain conditions, compared to either controlled-release morphine sulfate (CRMS) or Duragesic, can produce savings on total healthcare costs, total pharmacy costs, long-acting opioid costs, and often times short-acting opioid costs.
Additionally, a second study documented the fact that health-care costs were $17,580 higher among patients who switched therapy versus those who did not. The study documented that patients who begin therapy with controlled-release oxycodone are less likely to switch to another medication than those initially treated with either transdermal fentanyl or CRMS. These findings are of economic relevance, as health-care costs are significantly higher among patients who switch LAO therapy in comparison with those who do not.
In summary, a consistent pattern of pain reduction or continuing, stable pain control supported the analgesic efficacy of OxyContin tablets among patients with malignant and non-malignant pain syndromes. Use of OxyContin has been associated with significant improvements in patientreported outcomes, and limited available economic evidence suggests that OxyContin represents
a cost-effective use of scarce health resources.
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