As seen online:
“In summary, our findings show a high prevalence of unrecognized yet biochemically overt primary aldosteronism using current confirmatory diagnostic thresholds. They highlight the inadequacy of the current diagnostic approach that heavily relies on the ARR and, most important, show the existence of a pathologic continuum of nonsuppressible renin-independent aldosterone production that parallels the severity of hypertension. These findings support the need to redefine primary aldosteronism from a rare and categorical disease to, instead, a common syndrome that manifests across a broad severity spectrum and may be a primary contributor to hypertension pathogenesis.”
— from The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study - PMC as of 15 November 2025
Also see: Conn's and such